20 games played, by sport.
EPL The marquee game is Liverpool hosting Fulham at Anfield, where Liverpool are big favorites and need a bounce-back after a shaky start, though Fulham have yet to find the net in three matches and will be happy to grind out a nil-nil if their defense holds. Don't sleep on Arsenal traveling to Sunderland, since Arsenal are unbeaten and a win keeps their perfect start intact against a Sunderland side that's tough to break down at home. Chelsea are heavy favorites over Hull City at Stamford Bridge, so the real drama is whether Tottenham Hotspur can finally get a clean sheet against Everton in a match both sides need to avoid slipping further down the table.
MLB The marquee matchup is the Mets at the Yankees, a Subway Series getaway day tilt where New York's heart of the order gets tested against a Yankees club chasing a division crown while the Mets play spoiler down the stretch. Keep an eye on the Rays hosting the Astros with Tampa Bay heavily favored and holding one of the best records in baseball, and the Brewers-Reds game where Milwaukee's bullpen has been lights out in a 91-win season. Also worth a glance is the Phillies-Braves game getting held up by a rain delay before the Braves' starter even got through the first inning.
MLS The marquee game is Nashville SC at Inter Miami CF, where the visitors carry the league's best record into a Miami side still chasing a cleaner run of form. Nashville will look to spring the counterattack off a well-timed through ball, while Inter Miami's goal is to avoid a sitter in the box and keep pace with the Eastern Conference table. Elsewhere, Houston Dynamo FC's road trip to San Jose Earthquakes is a legit clash of top-of-table clubs, so don't be shocked if that one ends up tighter than a routine nil-nil.
NCAA Football The marquee tilt is Ohio State at Texas, a virtual pick 'em with the Buckeyes as one-point road dogs in a game that could set the tone for the whole College Football Playoff conversation. Don't sleep on Oklahoma at Michigan either, a physical, smashmouth matchup where whoever controls the line of scrimmage and time of possession probably walks out with the win. If you want garbage-time stats instead, plenty of the day's other games are lopsided enough that the favorites should cover easily and the over looks live by the fourth quarter.